DRP1 Blocking Peptide

General Information

Product

DRP1 Peptide

Description

Antigenic Blocking Peptide Dynamin-related Protein 1

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide within 450-490 on human DRP1 protein.

Accession #

GenBank: BAC06576.1

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20°C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q8K1M6

Overview

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.

Molecular Function

GTP-binding, Lipid-binding, Nucleotide-binding

Subcellular Location

Golgi apparatus; Peripheral membrane protein; peroxisome; Mitochondrion outer membrane; Clathrin-coated pit; synaptic vesicle membrane

Expression

Expressed in the cerebellum and in several regions of the cerebrum and diencephalon

Structure

Homotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Oligomerizes in a GTP-dependent manner to form membrane-associated tubules with a spiral pattern. Can also oligomerize to form multimeric ring-like structures.

Alternative Nomenclature

DLP1 antibody

dnm1l antibody

Dnm1p/Vps1p-like protein antibody

dnml1 antibody

DRP1 antibody

DVLP antibody

Dymple antibody

Dynamin 1 like antibody

Dynamin family member proline-rich carboxyl-terminal domain less antibody

Dynamin like protein antibody

Dynamin related protein 1 antibody

Dynamin-like protein 4 antibody

Dynamin-related protein 1 antibody

DYNIV 11 antibody

EMPF antibody

FLJ41912 antibody

HdynIV antibody

VPS1 antibody