|
General Information
|
|
|
Product
|
LILRB3 Peptide
|
|
Description
|
Antigenic Blocking Peptide Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
|
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
|
Peptide Description
|
Synthetic peptide taken within amino acid region 580-631 on human LILRB3 protein.
|
|
Accession #
|
NCBI: NP_001074919.2
|
|
Physical Properties
|
|
|
Quantity
|
250 µg
|
|
Volume
|
100 µl
|
|
Form
|
Antigenic Blocking Peptide
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
|
Protein
|
|
Uniprot #
|
O75022
|
|
Overview
|
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
|
|
Molecular Function
|
Receptor, Receptor activity, transmembrane signaling receptor activity
|
|
Subcellular Location
|
Cell membrane; Single-pass type I membrane protein
|
|
Expression
|
Detected in monocytes and B-cells
|
|
Alternative Nomenclature
|
CD85 antigen like family member A antibody
HL9 antibody
IL T5 antibody
Immunoglobulin like transcript 5 antibody
LIR 3 antibody
MGC138403 antibody
Monocyte inhibitory receptor HL9 antibody
PIRB antibody
|
| |
|
LILRB3 Antibody
LILRB3 Antibody FITC
LILRB3 Antibody BIOTIN
LILRB3 Positive Control
