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General Information
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Product
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NHERF-1 Peptide
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Description
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Antigenic Blocking Peptide Na(+)/H(+) exchange regulatory cofactor NHE-RF1 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide corresponding to amino acids within region 255-305 on human Na(+)/H(+) exchange regulatory cofactor NHE-RF1.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20?C for long term storage
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Application Protocol
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Immunodepletion, Immunocompetition
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Refer to competition assay protocol
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Protein
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Uniprot #
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O14745
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Overview
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Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
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Molecular Function
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beta-2 adrenergic receptor binding
beta-catenin binding
chloride channel regulator activity
dopamine receptor binding
gamma-aminobutyric acid transmembrane transporter activity
growth factor receptor binding
myosin II binding
PDZ domain binding
pho
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Subcellular Location
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Plasma membrane, cytoplasm
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Expression
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Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.
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Alternative Nomenclature
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EBP 50 antibody
Ezrin radixin moesin binding phosphoprotein 50 antibody
Na(+)/H(+) exchange regulatory cofactor NHE RF antibody
Na+/H+ exchange regulatory co factor antibody
NHERF 1 antibody
NHERF antibody
NHRF1_HUMAN antibody
NPHLOP2 antibody
Regulatory cofactor of Na(+)/H(+) exchanger antibody
Slc9a3r1 antibody
Sodium hydrogen exchanger regulatory factor 1 antibody
Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 1 antibody
Solute carrier family 9 isoform 3 regulatory factor 1 antibody
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NHERF-1 Antibody
NHERF-1 Antibody BIOTIN
NHERF-1 Antibody FITC
NHERF-1 Positive Control
