CDKN2A / p14ARF Blocking Peptide

Product no.: P-P14ARF.120
$155.00


General Information

 

 

Product

 

CDKN2A / p14ARF Peptide

Description

Antigenic Blocking Peptide partial tumor supressor p14ARF C-epitope

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide corresponding to C-terminal amino acids 94-111 of Human p14ARF.

 

Sequence:

QRLGQQPLPRRPGHDDGQ

Accession #

GenBank: AAC6069.1


Physical Properties

 

 

Quantity

 

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20C for long term storage


Application Protocol

Competition/Depletion assay

Refer to competition assay protocol


Protein

 

Uniprot #

 

Q8N726

Overview

Functions as a tumor supressor and has the ability to induce cell cycle arrest in the G1 and G2 phases.  Serves to induce G2 arrest and apoptosis in a p53-independent manner via preventing the activation of cyclin B1/CDC2 complexes.

Molecular Function

DNA binding, RNA binding, p53 binding, MDM2/MDM4 family protein binding

Subcellular Location

Nucleus

Structure

No interaction with cyclins, CDK1, CDK2, CDK4, CDK5 or CDK6.  Interacts with TBRG1, COMMD1, CDKN2AIP and E4F1.  Binds to BCL6, E2F1, HUWE1, MDM2, MYC, NPM1/B23, TOP1/TOPOI and UBE2I/UBC9.

Alternative Nomenclature

ARF antibody

CDK4 inhibitor p16 INK4 antibody

CDK4I antibody

CDKN 2A antibody

Cell cycle negative regulator beta antibody

CMM2 antibody

Cyclin dependent kinase 4 inhibitor A antibody

1/2/3 antibody

Cyclin dependent kinase inhibitor p16 antibody

INK4 antibody

Melanoma p16 inhibits CDK4 antibody

MLM antibody

MTS 1 antibody

p14 antibody

p16 antibody

p19 antibody

P19ARF antibody

TP16 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
CDKN2A / p14ARF Antibody CDKN2A / p14ARF Antibody
P14ARF-121AP $285.00 *
CDKN2A / p14ARF Antibody FITC CDKN2A / p14ARF Antibody FITC
P14ARF.120-FITC $375.00 *
CDKN2A / p14ARF Antibody BIOTIN CDKN2A / p14ARF Antibody BIOTIN
P14ARF.120-BIOTIN $375.00 *
CDKN2A / p14ARF Positive Control CDKN2A / p14ARF Positive Control
PC-P14ARF $200.00 *
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