|
General Information
|
|
|
Product
|
PD-L1 Peptide
|
|
Description
|
Antigenic Blocking Peptide Programmed cell death 1 ligand 1 Antibody
|
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
|
Peptide Description
|
Synthetic peptide taken within amino acid reigon 80-130 on human Progammed cell death 1 ligand 1 protein.
|
|
Accession #
|
NCBI: NP_054862
|
|
Physical Properties
|
|
|
Quantity
|
250 µg
|
|
Volume
|
100 µl
|
|
Form
|
Antigenic Blocking Peptide
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
|
Protein
|
|
Uniprot #
|
Q9NZQ7
|
|
Overview
|
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
|
|
Molecular Function
|
Receptor
|
|
Subcellular Location
|
Isoform 1 : Cell membrane; Single-pass type I membrane protein
Isoform 2 : Endomembrane system; Single-pass type I membrane protein
|
|
Expression
|
Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
|
|
Structure
|
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
|
|
Alternative Nomenclature
|
B7 H antibody
B7 homolog 1 antibody
CD 274 antibody
PD L1 antibody
PDCD1 ligand 1 antibody
PDCD1L1 antibody
PDCD1LG1 antibody
PDL 1 antibody
Programmed death ligand 1 antibody
RGD1566211 antibody
|
| |
|
PD-L1 Antibody
PD-L1 Antibody BIOTIN
PD-L1 Antibody FITC
PD-L1 Positive Control
