Robo3 Blocking Peptide

General Information

Product

Robo3 Peptide

Description

Antigenic Blocking Peptide Homer protein homolog 1 Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic Peptide

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q9Z214

Overview

ostsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.

Molecular Function

G-protein coupled glutamate receptor binding, identical protein binding, receptor binding

Subcellular Location

Cytoplasm, Cell junction

Expression

Highly expressed in cortex, Purkinje cells of the cerebellum, hippocampus, striatum and olfactory bulb. Isoform 1and isoform 3 are expressed in skeletal and cardiac muscle.

Structure

Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. Interacts with IFT57 and OPHN1. Isoform 1 and isoform 2 encode coiled-coil structures that mediate homo- and heteromultimerization.

Alternative Nomenclature

HGPPS antibody

HGPS antibody

RB inhibiting gene 1 antibody

Rbig1 antibody

Retinoblastoma inhibiting gene 1 antibody

Rig1 antibody

Roundabout axon guidance receptor homolog 3 antibody

Roundabout like protein 3 antibody