RIPK3 Blocking Peptide

Product no.: P-RIPK3.301
$155.00


General Information

 

 

Product

 

RIPK3 Peptide

Description

Antigenic Blocking Peptide Receptor-interacting Serine/Threonine-protein kinase 3 Antibody C-epitope

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic Peptide

Accession #

NCBINP_006862.2


Physical Properties

 

 

Quantity

 

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

C-epitope

Storage

-20C for long term storage


Application Protocol

Competition/Depletion assay

Refer to competition assay protocol


Protein

 

Uniprot #

 

Q9Y572

Overview

Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL.

Molecular Function

Kinase, Serine/threonine-protein kinase, Transferase

Subcellular Location

Cytoplasm, Cell membrane, Mitochondrion

Expression

Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.

Structure

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Alternative Nomenclature

Receptor interacting protein 3 antibody

Receptor interacting serine threonine kinase 3 antibody

Receptor-interacting protein 3 antibody

RIP 3 antibody

RIP like protein kinase 3 antibody

RIPK 3 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
RIPK3 Antibody RIPK3 Antibody
RIPK3-301AP $285.00 *
RIPK3 Antibody FITC RIPK3 Antibody FITC
RIPK3.301-FITC $375.00 *
RIPK3 Antibody BIOTIN RIPK3 Antibody BIOTIN
RIPK3.301-BIOTIN $375.00 *
RIPK3 Positive Control RIPK3 Positive Control
PC-RIPK3 $200.00 *
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