Slingshot homolog 1 Blocking Peptide

General Information

Product

Slingshot homolog 1 Peptide

Description

Antigenic Blocking Peptide Protein phosphatase Slingshot homolog 1 isoform 1 Antibody

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic Peptide

Accession #

NCBI:  NP_061857.3

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

Q8WYL5

Overview

Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.

Molecular Function

Hydrolase, protein phosphatase

Subcellular Location

Cytoplasm, cytoskeleton, cell projection, lamellipodium, cleavage furrow, midbody. (Note: Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at site of cell locomotion. Also localized to

Alternative Nomenclature

AW551225 antibody

Coro1c antibody

coronin, actin binding protein 1C antibody

Gm1394 antibody

Gm1395 antibody

Protein phosphatase Slingshot homolog 1 antibody

slingshot like 1 antibody

SSH1 antibody