EAAT2 Blocking Peptide

General Information

Product

EAAT2 Peptide

Description

Antigenic Blocking Peptide Excitatory amino acid transporter 2

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide corresponding to C terminal amino acids 550-574 of Human EAAT2. 

Sequence:

KVTLAANGKSADCSVEEEPWKREK

Accession #

NCBI:  NP_004162.2

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

P43004

Overview

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Molecular Function

Glutamate:sodium symporter activity, L-glutamate transmembrane transporter activity, sodium:dicarboxylate symporter activity

Subcellular Location

Membrane, multi-pass membrane protein

Alternative Nomenclature

Excitatory amino acid transporter 2 antibody

Excitotoxic amino acid transporter 2 antibody

Glial high affinity glutamate transporter antibody

GLT1 antibody

Glutamate aspartate transporter II antibody

Glutamate transporter 1 antibody

Glutamate/aspartate transporter II antibody

SLC1A2 antibody

Sodium dependent glutamate aspartate transporter 2 antibody

Solute carrier family 1 member 2 antibody