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General Information
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Product
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ETS1 associated protein II Peptide
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Description
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Antigenic Blocking Peptide tyrosyl-DNA phosphodiesterase 2 Antibody
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Verified Applications
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Immunocompetition, Immunodepletion
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Peptide Description
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Synthetic peptide taken within amino acid region 330-360 on human Tyrosyl-DNA phosphodiesterase protein.
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Accession #
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NCBI: NP_057698.2
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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O95551
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Overview
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DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue.
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Molecular Function
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5'-tyrosyl-DNA phosphodieseterase activity, magnesium ion binding, manganese ion binding, nuclease activity, transcription corepressor activity, single-stranded DNA binding
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Subcellular Location
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nucleus, PML body, cytoplasm
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Expression
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Widely expressed
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Alternative Nomenclature
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5'-tyrosyl-DNA phosphodiesterase antibody
AD 022 antibody
dJ30M3.3 antibody
EAP 2 antibody
ETS 1 associated protein 2 antibody
RP1-30M3.3 antibody
TRAF and TNF receptor associated protein antibody
TTRAP antibody
Tyr DNA phosphodiesterase 2 antibody
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ETS1 Associated protein II Antibody
ETS1 associated protein II Antibody FITC
ETS1 associated protein II Antibody BIOTIN
ETS1 associated protein II Positive Control
