TSG101 Blocking Peptide

Product no.: P-TSG101
$155.00


General Information

 

 

Product

 

TSG101 Peptide

Description

Antigenic Blocking Peptide Tumor susceptibility gene 101 protein Antibody

Verified Applications

Immunodepletion, Immunocompetition

Peptide Description

Synthetic peptide taken within amino acid region 330-390 on Tumor susceptibility gene 101 protein.


Physical Properties

 

 

Quantity

 

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Storage

-20C for long term storage


Application Protocol

 

Competition/Depletion assay

 

Refer to competition assay protocol


Protein

 

Uniprot #

 

Q99816

Overview

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Molecular Function

calcium-dependent protein binding

DNA binding

ligand-dependent nuclear receptor transcription coactivator activity

protein homodimerization activity

transcription corepressor activity

ubiquitin binding

ubiquitin protein ligase binding

virion binding

Subcellular Location

Cytoplasm

Membrane; Peripheral membrane protein

Nucleus

Late endosome membrane; Peripheral membrane protein

Expression

Heart, brain, placenta, lung, liver, skeletal, kidney and pancreas.

Alternative Nomenclature

ESCRT I complex subunit TSG101 antibody

TS101_HUMAN antibody

TSG 10 antibody

TSG 101 antibody

Tumor susceptibility gene 10 antibody

Tumor susceptibility gene 101 antibody

Tumor susceptibility protein antibody

Tumor susceptibility protein isoform 3 antibody

VPS23 antibody

   

Protein information supplied by UniProt.

 

Accessories

Product Note Status Price
TSG101 Antibody TSG101 Antibody
TSG101-101AP $285.00 *
TSG101 Antibody BIOTIN TSG101 Antibody BIOTIN
TSG101-BIOTIN $375.00 *
TSG101 Antibody FITC TSG101 Antibody FITC
TSG101-FITC $375.00 *
TSG101 Positive Control TSG101 Positive Control
PC-TSG101 $200.00 *
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