Usherin Blocking Peptide

General Information

Product

Usherin Peptide

Description

Antigenic Blocking Peptide Usherin isoform A Antibody N-epitope

Verified Applications

Immunocompetition, Immunodepletion

Peptide Description

Synthetic peptide taken within amino acid region 150-180 on usherin isoform A protein.

Accession #

NCBI:  NP_009054.5

Physical Properties

Quantity

250 µg

Volume

100 µl

Form

Antigenic Blocking Peptide

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Competition/Depletion assay

Refer to competition assay protocol

Protein

Uniprot #

O75445

Overview

Involved in hearing and vision.

Molecular Function

collagen binding, myosin binding

Subcellular Location

Cell projection › stereocilium membrane; Single-pass type I membrane protein

Expression

Present in the basement membrane of many, but not all tissues. Expressed in retina, cochlea, small and large intestine, pancreas, bladder, prostate, esophagus, trachea, thymus, salivary glands, placenta, ovary, fallopian tube, uterus and testis.

Structure

Interacts with collagen IV and fibronectin via its laminin EGF-like domains. Interaction with collagen may be required for stable integration into the basement membrane. Interacts with USH1C and WHRN. Interacts with NINL. Interacts with PDZD7

Alternative Nomenclature

dJ1111A8.1 antibody

US1 antibody

USH1A antibody

Usher syndrome type Ia protein antibody

Usher syndrome type-1A protein antibody

Usherin antibody