GTPase HRAS Antibody

General Information

Product

GTPase HRAS Antibody

Description

Affinity Purified Transforming p21 Ras Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 139-189 on human GTPase HRAS protein.

Accession #

NCBI:  NP_005334.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

1.00-1.25 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P01112 

Overview

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Molecular Function

GTP binding, Protein C-terminus binding

Subcellular Location

Cell membrane; Lipid anchor; Cytoplasmic side; Gogli appartus membrane; Lipid-anchor

Structure

In its GTP-bound form interacts with PLCE1. Interacts with TBC1D10C. Interacts with RGL3. Interacts with HSPD1. Found in a complex with at least BRAF, HRAS, MAP2K1, MAPK3 and RGS14. Interacts (active GTP-bound form) with RGS14 (via RBD 1 domain).

Alternative Nomenclature

c bas/has antibody

c has/bas p21 protein antibody

c ras Ki 2 protein antibody

c-H-ras antibody

CTLO antibody

G1III6 N ras antibody

GTP and GDP binding peptide B antibody

GTPase HRas antibody

H Ras 1 antibody

H ras oncogene antibody

H RasIDX antibody

Ha Ras1 proto oncoprotein antibody

HAMSV antibody

Harvey rat sarcoma viral oncoprotein antibody

HRAS1 antibody

K ras antibody

N ras antibody

p19 H RasIDX protein antibody

p21ras antibody

Ras family small GTP binding protein H Ras antibody

RASH1 antibody

Transformation gene oncogene HAMSV antibody

Transforming protein p21 antibody

v Ha ras Harvey rat sarcoma viral oncogene homolog antibody

VH Ras antibody