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General Information
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Product
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Adenylate Cyclase 1 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rabbit, Rat
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Immunogen
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Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein.
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Accession #
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GenBank: AAC29478
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55- 0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500. Detects a band 127-10 kDa
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Protein
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Uniprot #
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O88444
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Overview
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This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina
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Molecular Function
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ATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-binding
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Subcellular Location
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Membrane; Multi-pass membrane protein. Cytoplasm
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Expression
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Expressed throughout inner ear development. Brain, retina and adrenal medulla.
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Structure
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Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains
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Alternative Nomenclature
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3'5' cyclic AMP synthetase antibody
ADCY1 antibody
adenyl cyclase antibody
Adenylate cyclase 1 antibody
ATP pyrophosphate lyase antibody
Brain adenylate cyclase 1 antibody
Ca(2+)/calmodulin activated adenylyl cyclase antibody
EC 4.6.1.1 antibody
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Adenylate cyclase 1 Antibody FITC
Adenylate cyclase 1 Antibody BIOTIN
Adenylate cyclase 1 Blocking Peptide
Adenylate cyclase 1 Positive Control
