Adenylate cyclase 1 Antibody

Product no.: PAC-101AP

General Information

 

 

Product

 

Adenylate Cyclase 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rabbit, Rat

Immunogen

Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein.

Accession #

GenBank: AAC29478 


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55- 0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500. Detects a band 127-10 kDa


Protein

 

Uniprot #

 

O88444

Overview

This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina

Molecular Function

ATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-binding

Subcellular Location

Membrane; Multi-pass membrane protein. Cytoplasm

Expression

Expressed throughout inner ear development. Brain, retina and adrenal medulla.

Structure

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains

Alternative Nomenclature

3'5' cyclic AMP synthetase antibody

ADCY1 antibody

adenyl cyclase antibody

Adenylate cyclase 1 antibody

ATP pyrophosphate lyase antibody

Brain adenylate cyclase 1 antibody

Ca(2+)/calmodulin activated adenylyl cyclase antibody

EC 4.6.1.1 antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
Adenylate cyclase 1 Antibody FITC Adenylate cyclase 1 Antibody FITC
PAC1-FITC
Adenylate cyclase 1 Antibody BIOTIN Adenylate cyclase 1 Antibody BIOTIN
PAC1-BIOTIN
Adenylate cyclase 1 Blocking Peptide Adenylate cyclase 1 Blocking Peptide
P-PAC1
Adenylate cyclase 1 Positive Control Adenylate cyclase 1 Positive Control
PC-PAC1
Display accessory details

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