PACAP Antibody

Product no.: PACA-101AP
$285.00


General Information

 

 

Product

 

PACAP Antibody

Description

Affinity Purified Pituitary adenylate cyclase-activating polypeptide Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein.


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:50,000

Immunohistochemistry 1:50-1:250

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000


Protein

 

Uniprot #

 

P18509

Overview

Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.

Molecular Function

neuropeptide hormone activity

peptide hormone receptor binding

pituitary adenylate cyclase activating polypeptide activity

pituitary adenylate cyclase-activating polypeptide receptor binding

receptor binding

signal transducer activity, downstream of receptor

Subcellular Location

Secreted

Expression

Interacts with ADCYAP1R1 (via N-terminal extracellular domain).

Structure

Belongs to the glucagon family.

Alternative Nomenclature

adenylate cyclase activating polypeptide 1 (pituitary) antibody

PACAP antibody

PACAP-related peptide antibody

Pituitary adenylate cyclase-activating polypeptide 27 antibody

Pituitary adenylate cyclase-activating polypeptide 38 antibody

Pituitary adenylate cyclase-activating polypeptide antibody

prepro-PACAP antibody

PRP-48 antibody

   

Protein information supplied by UniProt.

 

Accessories

Product Note Status Price
PACAP Antibody BIOTIN PACAP Antibody BIOTIN
PACA-BIOTIN $375.00 *
PACAP Antibody FITC PACAP Antibody FITC
PACA-FITC $375.00 *
PACAP Blocking Peptide PACAP Blocking Peptide
P-PACA $155.00 *
PACAP Positive Control PACAP Positive Control
PC-PACA $200.00 *
Display accessory details

Browse these categories as well: Neuropeptides & Hormones, Primaries