Phospho-alpha Actinin 4 (S159) Antibody

General Information

Product

Phospho-alpha Actinin 4 (S159) antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic phospho-peptide, corresponding to a region within amino acid regions 140-190 of Human alpha Actinin 4 conjugated to a carrier protein.

Accession #

NCBI:  NP_004915

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500 Predicted molecular weight: 105kDa

Protein

Uniprot #

O43707

Overview

F-actin cross-linking protein that anchors variety of intracellular structures.  Bundling protein involved in vesicular trafficking via its association with the CART complex.

Molecular Function

Protein Transport; Actin-binding

Subcellular Location

Cytoplasmic mRNP granules containing untranslated mRNAs.  Colocalizes with actin stress fibers.

Expression

Induced by pI3 kinase inhibitor wortmannin or by cytochalasin D.  Localized in the nucleus.

Structure

Widely Expressed

Alternative Nomenclature

actinin 4 antibody

Actinin alpha 4 antibody

ACTN 4 antibody

DKFZp686K23158 antibody

F actin cross linking protein antibody

Focal segmental glomerulosclerosis 1 antibody

FSGS 1 antibody