General Information
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Product
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Phospho-alpha Actinin 4 (S159) antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic phospho-peptide, corresponding to a region within amino acid regions 140-190 of Human alpha Actinin 4 conjugated to a carrier protein.
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Accession #
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NCBI: NP_004915
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.62 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation |
1:200 |
Western Blot
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1:500 Predicted molecular weight: 105kDa
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Protein
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Uniprot #
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O43707
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Overview
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F-actin cross-linking protein that anchors variety of intracellular structures. Bundling protein involved in vesicular trafficking via its association with the CART complex.
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Molecular Function
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Protein Transport; Actin-binding
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Subcellular Location
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Cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers.
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Expression
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Induced by pI3 kinase inhibitor wortmannin or by cytochalasin D. Localized in the nucleus.
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Structure
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Widely Expressed
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Alternative Nomenclature
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actinin 4 antibody
Actinin alpha 4 antibody
ACTN 4 antibody
DKFZp686K23158 antibody
F actin cross linking protein antibody
Focal segmental glomerulosclerosis 1 antibody
FSGS 1 antibody
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