Phospho-Aquaporin 2 Antibody

General Information

Product

Phospho-Aquaporin 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-240 on rat Aquaporin 2 protein.  Phosphorylated Serine 218 residue.

Accession #

NCBI:  NP_037041

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.62 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P34080

Overview

Forms a water-specific channel that provies the plasma mebranes of red cells and kidney proximal tubules with water permeability.

Molecular Function

Transport

Subcellular Location

Apical cell membrane; Multiplass membrane protein; Basolateral cell membrane

Expression

Renal collecting tubules

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

ADH water channel antibody

Aquaporin 2 collecting duct antibody

Aquaporin-CD antibody

Aquaporine 2 antibody

Collecting duct water channel protein antibody

MGC34501 antibody

Water channel aquaporin 2 antibody

Water channel protein for renal collecting duct antibody

WCHCD antibody