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General Information
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Product
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PAX5 Antibody
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Description
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Affinity Purified Paired box protein PAX-5 Antibody Mid-Region
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse
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Immunogen
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Synthetic peptide taken within amino acid region 120-170 on human PAX5 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.65-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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Mid-Region
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q02548
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Overview
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May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
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Molecular Function
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Developmental protein, RNA polymerase II core promoter proximal region sequence-specific DNA binding
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Subcellular Location
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Nucleus
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Expression
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Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
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Structure
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Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4. Interacts with ETS1, altering its DNA-binding properties.
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Alternative Nomenclature
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B cell lineage specific activator antibody
BSAP antibody
EBB-1 antibody
KLP antibody
Paired box 5 antibodyPAX 5 antibody
Transcription factor PAX 5 antibody
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PAX5 Antibody FITC
PAX5 Antibody BIOTIN
PAX5 Blocking Peptide
PAX5 Positive Control
