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General Information
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Product
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5HT1B Receptor Positive Control
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Description
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Western Blot Positive Control 5 Hydroxytryptamine 1B receptor
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Verified Applications
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WB
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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P28334
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Overview
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G-protein coupled receptor for serotonin (5-hydroxytryptamine). Functions as a receptor for various drugs which cause conformational change upon ligand binding that triggers signaling via guanine nucleo-tide binding proteins and modulation of down-stream effectors like adenylate cyclase. Inhibits adenylate cyclase activity and activates phosphatidylinositol-calcium second messenger system that regulates release of intracellular Calcium ions.
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Molecular Function
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Drug binding, serotonin receptor activity, serotonin binding
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Subcellular Location
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Cell membrane; Multi-pass protein
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Structure
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Homodimer. Heterodimer with HTR1D
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Alternative Nomenclature
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HTR1DB antibody
S12 antibody
Serotonin 1D beta receptor antibody
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5HT1B Antibody
5HT1B Antibody FITC
5HT1B Blocking Peptide
5HT1B Antibody BIOTIN
