BST2 Positive Control

General Information

Product

BST2 Positive Control

Description

Western Blot Positive Control Bonemarrow stromal antigen 2 

Verified Applications

WB

Immunogen

Purified Protein

Accession #

GenBank:  BAD96844

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q10589

Overview

IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.

Molecular Function

Antiviral defense; B-cell activation; Immunity; Innate immunity

Subcellular Location

Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane

Expression

Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors.

Structure

Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.

Alternative Nomenclature

Bone marrow stromal antigen 2 antibody

Bone marrow stromal cell antigen 2 antibody

BST 2 antibody

CD 317 antibody

CD317 antigen antibody

HM1.24 antigen antibody

NPC A 7 antibody

Tetherin antibody