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General Information
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Product
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CCR5 Positive Control
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Description
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Western Blot Positive Control Chemokine receptor type 5
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Verified Applications
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WB
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Immunogen
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Purified Protein
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Accession #
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NCBI: AAB65720.1
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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P51681
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Overview
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Receptor for several inflammatory C-C chemokines. May play a role in control of granulocytic lineage proliferation or differentiation.
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Molecular Function
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actin binding; C-C chemokin binding; GPCR; Receptor; Transducer; Host-virus interaction
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Subcellular Location
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Cell membrane; Mulipass membrane protein.
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Expression
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Spleen, Thymus, myeloid cell line THP-1, promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Lesser expressed in peripheral blood leukocytes, small intestine and ovary and lung.
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Structure
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Interacts with PRAF2, HIV-1 surface protein gp120. Glycosylation on Ser-6 is required for binding with CCL4.
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Alternative Nomenclature
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AM4 7 antibody
CCCKR 5 antibody
CD 195 antibody
CHEMR13 antibody
HIV 1 Fusion Coreceptor antibody
IDDM22 antibody
MIP-1 alpha receptor antibody
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CCR5 Antibody
CCR5 Antibody FITC
CCR5 Blocking Peptide
CCR5 Antibody BIOTIN
