ADCY5 Positive Control

Product no.: PC-PAC5

$200.00

Description
Publications

General Information
Product	ADCY5 Positive Control
Description	Western Blot Positive Control Adenylyl cyclase type 5
Verified Applications	WB
Accession #	GenBank: M96159.1
Physical Properties
Quantity	5 Applications
Volume	Inquire
Form	Western Blot Positive Control
Concentration	The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel.
Storage	-20⁰C for long term storage

Protein
Uniprot #	Q04400
Overview	Membrane bound calcium-inhibitable adenylyl cyclase.
Molecular Function	Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding
Subcellular Location	Membrane; Multi-pass membrane protein; Cell projection; cilium
Structure	Part of a complex containing AKAP5, ADCY6, PDE4C and PKD2. Interacts with RAF1.
Alternative Nomenclature	AC 5 antibody Adcy5 antibody Adenylate cyclase type V antibody Adenylyl cyclase 5 antibody ATP pyrophosphate-lyase 5 antibody

Protein information supplied by UniProt

Fabgennix ADCY5 Antibody has been used in 9 Publications

Akkerman, Sven et al. “PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?” Ed. Patrizia Campolongo. PLoS ONE 9.11 (2014): e111692.

PMC4221101

Western Blot; Rat

Kwon, Ronald Y. et al. “Primary Cilium-Dependent Mechanosensing Is Mediated by Adenylyl Cyclase 6 and Cyclic AMP in Bone Cells.” The FASEB Journal 24.8 (2010): 2859–2868. PMC2909282

Confocal Microscopy, Immunofluorescence; Human

Masyuk, Anatoliy I. et al. “Cholangiocyte Primary Cilia Are Chemosensory Organelles That Detect Biliary Nucleotides via P2Y12 Purinergic Receptors.”American Journal of Physiology - Gastrointestinal and Liver Physiology295.4 (2008): G725–G734. PMC2575915

Confocal Microscopy, Immunofluorescence; Rat

Ortiz-Capisano, M. Cecilia, et al. "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." Hypertension 49.3 (2007): 618-624.PMID17190869

Confocal Microscopy, Immunofluorescence, Western Blot; Rat

Wang, Shyi-Chyi et al. “Regulation of Type V Adenylate Cyclase by Ric8a, a Guanine Nucleotide Exchange Factor.” The Biochemical Journal 406.Pt 3 (2007): 383–388. PMC2049038

Immunocytochemistry; Rat

Ivanov, Alexander et al. “Adenylate Cyclase 5 and KCa1.1 Channel Are Required for EGFR up-Regulation of PCNA in Native Contractile Rat Basilar Artery Smooth Muscle.” The Journal of Physiology 570.Pt 1 (2006): 73–84. PMC1464296

Confocal Microscopy, Immunofluorescence, Western Blot; Rat

Grünberger, Christian, et al. "The Calcium Paradoxon of Renin Release Calcium Suppresses Renin Exocytosis by Inhibition of Calcium-Dependent Adenylate Cyclases AC5 and AC6." Circulation research 99.11 (2006): 1197-1206.

PMID17068292

Western Blot; Rat

Masyuk, Anatoliy I. et al. “Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them into Intracellular Ca2+ and cAMP Signaling.”Gastroenterology 131.3 (2006): 911–920. PMC1866168

Confocal Microscopy, Immunofluorescence; Rat

Kolachala, Vasantha, et al. "Interferon-γ down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." Journal of Biological Chemistry 280.6 (2005): 4048-4057. PMID15550390

Western Blot; Human

Publishing research using PAC-501AP? Please let us know, we can cite the reference in this datasheet.