SIRT1 Antibody Positve Control

Product no.: PC-SIR1

Description

General Information
Product	SIRT1 Positive Control
Description	Western Blot Positive Control NAD-dependent protein deacetylase sirtuin-1 isoform 1 Antibody
Verified Applications	WB
Accession #	NCBI: NP_062786.1
Physical Properties
Quantity	5 Applications
Volume	Inquire
Concentration	The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel.
Form	Western Blot Positive Control
Storage	-20⁰C for long term storage
Application Protocol
Western Blot	1:500
Protein
Uniprot #	Q923E4
Overview	NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autphagy.
Subcellular Location	Nucleus, PML body, cytoplasm. (Nucleus: Recruited to the nuclear bodies via its interaction with the PML. Colocalized with APEX1 in nucleus. May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane. Shuttles between nucleus and cytoplasm).
Expression	Widely expressed. Weakly expressed in liver and skeletal muscle.
Alternative Nomenclature	75SirT1 antibody HST2, S. cerevisiae, homolog of antibody NAD dependent deacetylase sirtuin 1 antibody Regulatory protein SIR2 homolog 1 antibody SIR2 like protein 1 antibody SIR2, S.cerevisiae, homolog-like 1 antibody SIR2ALPHA antibody SIR2L1 antibody SirtT1 75 kDa fragment antibody Sirtuin type 1 antibody

Protein information supplied by UniProt