VPS26 Positive Control

General Information

Product

VPS26 Positive Control

Description

Western Blot Positive Control Vacuolar protein sorting-associated protein 26A

Verified Applications

WB

Immunogen

Purified Protein

Physical Properties

Quantity

5 Applications

Volume

Inquire

Form

Western Blot Positive Control

Storage

-20⁰C for long term storage

Application Protocol

Western Blot

1:500

Protein

Uniprot #

O75436

Overview

Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3.

Molecular Function

protein transporter activity

Subcellular Location

cytoplasm, endosome membrane, preipheral membrane protein (Note: Localizes to tubular profiles adjacent to endosomes. Predominantly found in early not late endosomes)

Expression

Down-regulated in Alzheimer disease. No polymorphism or variant is however associated with Alzheimer disease for VPS26A.

Alternative Nomenclature

FLJ12930 antibody

FLJ12930 antibody

HB 58 antibody

Hbeta 58 antibody

Hbeta 58 homolog antibody

MGC94168 antibody

PEP 8A antibody

Vacuolar protein sorting 26 A antibody

Vacuolar protein sorting 26 homolog A yeast antibody

Vacuolar protein sorting associated protein 26A antibody

Vesicle protein sorting 26A antibody

VPS 26 antibody

VPS 26A antibody