PDE1C Antibody

General Information

Product

PDE1C Antibody

Description

Affinity Purified Pan Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A) Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene. The sequence was taken within amino acid region 10-70.

Accession #

GenBank: U40371.1 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

This antibody is labeled as C-epitope, because it was taken closer to the C-terminus in relation to our other PDE1C antibody (PD1C-301AP).

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:40-1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:40-1:100

Immunofluorescence

1:200

Immunohistochemistry

1:40-1:100

Immunoprecipitation

1:200

Western Blot

1:500-1:2,000

Protein

Uniprot #

Q14123

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.

Molecular Function

Hydrolase, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion  binding

Subcellular Location

Cytosol

Expression

Expressed in several tissues, including brain and heart.

Structure

Homodimer

Alternative Nomenclature

5''-cyclic nucleotide phosphodiesterase 1C antibody

Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1C antibody

Cam PDE 1C antibody

HCAM3 antibody

HSPDE1C1A antibody

Human 3'5' cyclic nucleotide Phosphodiesterase antibody

PDE 1C antibody

Phosphodiesterase 1C antibody

Phosphodiesterase 1C calmodulin dependent antibody