PDE2A Antibody

Product no.: PD2A-101AP
$320.00


General Information

 

 

Product

 

PDE2A Antibody

Description

Affinity Purified Phosphodiesterase 2A, cGMP-stimulated Antibody C-epitope

Verified Applications

CM, ELISA, FRET, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique C-terminal amino acid sequence on PDE2A gene.

Specificity This antibody will label PDE2A1, PDE2A2, PDE2A3 and PDE2A4 variants.

Accession #

GenBank: EAW74861.1

Product Notes This antibody has been validated by peptide competition in the publication Liu et al [2009].


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20C for long term storage


Application Protocol

 

Confocal Microscopy

 

1:250-1:1,000

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250-1:1,000

Immunofluorescence

1:150-1:1,000

Immunohistochemistry

1:250-1:1,000

Immunoprecipitation

1:200

Western Blot

1:250-1:1,000


Protein

 

Uniprot #

 

UPI000003B340

Overview

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Molecular Function

Hydrolase, cAMP, cGMP, Metal-binding, Angiogenesis

Subcellular Location

Multi-pass membrane protein

Expression

bundant in adipose tissues.

Structure

Interacts with PIK3CG. Interacts with RAPGEF3 and PIK3R6.

Alternative Nomenclature

5''-cyclic phosphodiesterase antibody

cGMP dependent 3'5' cyclic phosphodiesterase antibody

cGMP stimulated phosphodiesterase 1 antibody

cGMP stimulated phosphodiesterase 4 antibody

cGMP-dependent 3'' antibody

CGS PDE antibody

Cyclic GMP stimulated phosphodiesterase antibody

PDE 2A antibody

PDE 2A1 antibody

PDE 2A4 antibody

PDE2A antibody

Phosphodiesterase 2A cGMP stimulated antibody

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
PDE2A Antibody FITC PDE2A Antibody FITC
PD2A.c-FITC $375.00 *
PDE2A Antibody BIOTIN PDE2A Antibody BIOTIN
PD2A.c-BIOTIN $375.00 *
PDE2A Blocking Peptide PDE2A Blocking Peptide
P-PD2A.c $155.00 *
PDE2A Positive Control PDE2A Positive Control
PC-PD2A $220.00 *
Display accessory details

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