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General Information
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Product
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PDE7A Antibody
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Description
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Affinity Purified cAMP-specific cyclic nucleotide phosphodiesterase PDE7A3 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic cyclic peptide common to all PDE7A variants
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| Specificity |
This antibody is specific for PDE7A variants and will not cross-react with PDE7B or other PDE family members. |
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Accession #
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GenBank: AAK57640.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.50-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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| Immunohistocheistry |
1:100 |
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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Q13946
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
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Molecular Function
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3', 5' -cyclic-AMP phosphodiesterase activity
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Subcellular Location
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Isoform PDE7A1 : Cytoplasm › cytosol, Isoform PDE7A2: Cytoplasm
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Expression
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PDE7A1 is found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. PDE7A2 is found abundantly in skeletal muscle and at low levels in heart.
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Structure
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Interacts with CBFA2T3
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Alternative Nomenclature
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HCP 1 antibody
P2A antibody
PDE 7 antibody
PDE1/PDE2 yeast human complement of antibody
PDE7A antibody
Phosphodiesterase 7A antibody
Phosphodiesterase isozyme 7 antibody
Rolipram insensitive phosphodiesterase type 7 antibody
TM 22 antibody
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PDE7A Antibody FITC
PDE7A Antibody BIOTIN
PDE7A Blocking Peptide
PDE7A Positive Control
