PD-L1 Antibody

Product no.: PDL1-101AP

$285.00

Description

General Information
Product	PD-L1 Antibody
Description	Affinity Purified Programmed cell death 1 ligand 1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey Predicted: Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid reigon 80-130 on human Progammed cell death 1 ligand 1 protein.
Accession #	NCBI: NP_054862
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Purification Method	Immobilized antigen affinity chromatography
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:100
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	Q9NZQ7
Overview	Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Molecular Function	Receptor
Subcellular Location	Isoform 1 : Cell membrane; Single-pass type I membrane protein Isoform 2 : Endomembrane system; Single-pass type I membrane protein
Expression	Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
Structure	Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Alternative Nomenclature	B7 H antibody B7 homolog 1 antibody CD 274 antibody PD L1 antibody PDCD1 ligand 1 antibody PDCD1L1 antibody PDCD1LG1 antibody PDL 1 antibody Programmed death ligand 1 antibody RGD1566211 antibody

Protein information supplied by UniProt