PGCF Antibody

General Information

Product

PGCF Antibody Affinity Purified

Description

Affinity Purified Guanylyl Cyclase F Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase F protein.

Accession #

GenBank: L36029.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

P51842

Overview

Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.

Molecular Function

Lyase

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Expressed only in the eye.

Structure

Belongs to the adenylyl cyclase-class-4/guanylyl cyclase family.  Contains 1 guanylate cyclase domain.  Contains 1 protein kinase domain.

Alternative Nomenclature

Particulate Guanylate Cyclase F antibody