PGCG Antibody

General Information

Product

PGCG Antibody

Description

Affinity Purified Guanylyl Cyclase G Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase G protein.

Accession #

GenBank: AF024622.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

P55205

Overview

Binds to a yet not identified ligand.

Possible role in processes such as water and electrolyte balance, and muscle contraction.

Molecular Function

Lyase, Receptor

Subcellular Location

Isoform 1:  Cell membrane; Single-pass type I membrane protein.  Isoform 2:  Cytoplasm

Expression

Expressed in lung, kidney and skeletal muscle. Low levels in intestine.

Structure

Homodimer or heterodimer with NPR1.

Alternative Nomenclature

CYGF antibody

GC F antibody

guanylate cyclase 2D-like, membrane (retina-specific) antibody

Guanylate cyclase 2F antibody

GUC2DL antibody

GUC2F antibody

Gucy2f antibody

RETGC-2 antibody

retinal antibody

Rod outer segment membrane guanylate cyclase 2 antibody

ROS-GC2 antibody