PINK1 Antibody

Product no.: PINK1-101AP

$285.00

Description

General Information
Product	PINK1 Antibody
Description	Affinity Purified Serine/Threonine-protein kinase PINK1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on human PINK1 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q9BXM7
Overview	During cellular stress it serves to protect against mitochondrial dysfunction through the phosphorylation of mitochondrial proteins. Uses selective autophagy to clear mitochondria that has been damaged.
Molecular Function	Kinase, Serine/threonine-protein kinase, Transferase
Subcellular Location	Mitochondrion outer membrane; Single-pass membrane protein, Cytoplasm
Expression	Expression is detected at high levels in the heart, skeletal muscles and testis. Expression is detected at lower levels in the brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine.
Structure	Interacts with PARK2 and FBXO7
Alternative Nomenclature	BRPK antibody FLJ27236 antibody mitochondrial antibody PARK 6 antibody Phosphatase and Tensin Homolog antibody PINK 1 antibody Protein kinase BRPK antibody PTEN induced putative kinase 1 antibody Serine/threonine-protein kinase PINK1 antibody

Protein information supplied by UniProt