Phospho-JAK1 Antibody

Product no.: PJAK1-140AP

$375.00

General Information
Product	Phospho-JAK1 Antibody
Description	Affinity Purified Phosphorylated Tyrosine-protein kinase JAK1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1000-1050 on human JAK1 protein. Phosphorylated 1034 & 1035 tyrosine residues.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Modification	Phosphorylated tyrosine 1034 & 1035.
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:100
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	P23458
Overview	Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway (PubMed:7615558). Kinase partner for the interleukin (IL)-2 receptor (PubMed:11909529).
Molecular Function	Kinase, Transferase, Tyrosine-protein kinase
Expression	Endomembrane system; Peripheral membrane protein
Structure	Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. Contains 1 FERM domain. Contains 2 protein kinase domains. Contains 1 SH2 domain.
Alternative Nomenclature	JAK 1 JAK 1A JAK 1B Janus kinase 1 (a protein tyrosine kinase) Janus kinase 1 JTK3 Tyrosine protein kinase JAK1

Protein information supplied by UniProt