Phospho-Smad1 Antibody

General Information

Product

Phospho Smad1 Antibody

Description

Affinity Purified Protein mothers against dpp Antibody

Verified Applications

ELISA, ICC/IF, WB

Host

Rabbit

Species Cross Reactivity

Drosophila melanogaster

Immunogen

Synthetic peptide taken within amino acid region 405-455 on D. melanogaster Mothers against dpp protein.

Accession #

NCBI:  NP_477017.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.0 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P42003

Overview

Required for the function of decapentaplegic. May play an important role in mediating Dpp signaling. Involved in the BMP signaling pathway.

Molecular Function

DNA binding; RNA polymerase II activating transcription factor; Transcription regulatory region sequence-specific activity; Transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity

Subcellular Location

Cytoplasm; Nucleus

Expression

Is detected in all developmental stages, though it appears most abundant in pupae, adult stages and early embryos. Its abundance decreases throughout embryonic and larval development and then returns to high levels in pupae and adult females.

Structure

Homotrimer

Alternative Nomenclature

BSP 1 antibody

Dwarfin A antibody

DwfA antibody

JV 41 antibody

MAD homolog 1 antibody

MAD mothers against decapentaplegic homolog 1 antibody

Mad related protein 1 antibody

MADR1 antibody

Mothers against DPP homolog 1 antibody

Sma and Mad related protein 1 antibody

SMAD 1 antibody

Spinal muscular atrophy distal with upper limb predominance antibody

TGF beta signaling protein 1 antibody

Transforming growth factor beta signaling protein 1 antibody