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General Information
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Product
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PODXL1 Antibody
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Description
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Affinity Purified Podocalyxin isoform 1 Antibody N-epitope
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Verified Applications
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DB, ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding amino acid region 200-250 on human PODXL protein.
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| Specificity |
This antibody will react with PODXL isoform 1 and will not detect PODXL isoform 2. |
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Accession #
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NCBI: NP_001018121.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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Dot Blot
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1:4,000
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ELISA
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1:4,000
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| Immunohistochemistry |
1:50-1:100 |
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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O00592
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Overview
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Involved in the regulation of both adhesion and cell morphology and cancer progression. Funciton as an anti-aging adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion.
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Subcellular Location
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Apical cell membrane, Cell projection, Membrane
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Expression
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Glomerular epithelium cell (podocyte)
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Structure
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Monomer; when associated with the membrane raft. Oligomer; when integrated in the apical membrane.
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Alternative Nomenclature
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GCTM-2 antigen antibody
Gp200 antibody
MGC138240 antibody
PC antibody
PCLP antibody
PCLP1 antibody
Pcx antibody
Podocalyxin antibody
Podocalyxin-like protein 1 antibody
Podxl antibody
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PODXL1 Antibody FITC
PODXL1 Antibody BIOTIN
PODXL1 Blocking Peptide
PODXL Positive Control
