POMT1 Antibody FITC

General Information

Product

POMT1 Antibody FITC-Conjugated

Description

FITC-Conjugated Protein O-mannosyl-transferase 1 isoform a Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-460 on human POMT1 protein.

Accession #

NCBI:  NP_009102.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

FITC-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunohistochemistry

1:50

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9Y6A1

Overview

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient.

Molecular Function

mannosyltransferase activity, metal ion binding

Subcellular Location

Endoplasmic reticulum membrane, multi-pass membrane protein

Expression

Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver.

Alternative Nomenclature

Dolichyl phosphate mannose protein mannosyltransferase 1 antibody

LGMD2K antibody

POMT 1 antibody

Protein O mannosyl transferase 1 antibody