PREX1 Antibody

Product no.: PREX-101AP
$295.00
$265.00


General Information

 

 

Product

 

PREX1 Antibody

Description

Affinity Purified Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.

 

Sequence:

QEEDQADSAFPLLSLGPRLSLC


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Immunohistochemistry 1:50-1:150
Immunoprecipitation 1:500

Western Blot

1:500-1:750


Protein

 

Uniprot #

 

Q8TCU6

Overview

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Molecular Function

enzyme binding, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding

Subcellular Location

Cytoplasm, cell membrane

Expression

Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues.

Alternative Nomenclature

4 antibody

5)-dependent Rac exchanger 1 antibody

P REX1 antibody

PtdIns(3,4,5) dependent Rac exchanger 1 antibody

SET domain containing 6 antibody

Setd6 antibody

   

Protein information supplied by UniProt

 

Accessories

Product Note Status Price
PREX1 Antibody FITC PREX1 Antibody FITC
PREX-FITC $350.00 *
PREX1 Antibody BIOTIN PREX1 Antibody BIOTIN
PREX-BIOTIN $350.00 *
PREX1 Blocking Peptide PREX1 Blocking Peptide
P-PREX $145.00 *
PREX1 Positive Control PREX1 Positive Control
PC-PREX1 $185.00 *
Display accessory details

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