PREX2 Antibody BIOTIN

Product no.: PREX2-BIOTIN
$350.00


batch-8-clean_8

General Information

 

 

Product

 

PREX2 Antibody BIOTIN-Conjugated

Description

BIOTIN-Conjugated PtdIns(3,4,5)-dependent Rac exchanger 2a Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 720-900 on PREX2 protein.

Accession #

GenBank:  DAA05334.1


Physical Properties

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

BIOTIN-Conjugated

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750


Protein

 

Uniprot #

 

Q70Z35

Overview

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Molecular Function

Rac GTPase activator activity, Rac guanyl-nucleotide exchange factor activity

Expression

Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.

Alternative Nomenclature

4 antibody

5)-dependent Rac exchanger 2 antibody

5-trisphosphate-dependent Rac exchanger 2 protein antibody

DEP domain-containing protein 2 antibody

DEP.2 antibody

Phosphatidylinositol 3 antibody

PtdIns(3,4,5)-dependent Rac exchanger 2 antibody

Protein information supplied by UniProt
 


Accessories

Product Note Status Price
PREX2 Blocking Peptide PREX2 Blocking Peptide
P-PREX2 $145.00 *
PREX2 Antibody PREX2 Antibody
PREX2-201AP $265.00 *
PREX2 Antibody FITC PREX2 Antibody FITC
PREX2-FITC $350.00 *
PREX2 Positive Control PREX2 Positive Control
PC-PREX2 $185.00 *
Display accessory details