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General Information
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Product
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Brk Antibody
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Description
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Affinity Purified Protein-Tyrosine Kinase 6 isoform Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 400-450 on mouse Protein-Tyrosine Kinase 6 isoform.
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Accession #
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NCBI: NP_033210
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polylclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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Q64434
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Molecular Function
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ATP binding
identical protein binding
non-membrane spanning protein tyrosine kinase activity
protein tyrosine kinase activity
signaling receptor binding
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Subcellular Location
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Nucleus, Cytoplasm, Membrane, Ruffle
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Expression
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Expressed only in epithelial tissues, including the skin and lining of the alimentary canal. Restricted to the cell layers immediately above the proliferative cell zone in these epithelia.
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Structure
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The SH3 domain plays a major role in substrate interactions. The SH2 domain of PTK6 plays a role in protein-protein interactions, but is likely more important for the regulation of catalytic activity (By similarity).
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Alternative Nomenclature
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Breast tumor kinase antibody
Protein tyrosine kinase 6 antibody
Ptk6 antibody
Tyrosine-protein kinase BRK antibody
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Brk Antibody BIOTIN
Brk Positive Control
Brk Blocking Peptide
Brk Antibody FITC
