DNA polymerase eta Antibody

Product no.: RAD30-101AP
$295.00
$265.00


General Information

 

 

Product

 

DNA polymerase eta Antibody

Description

Affinity Purified Chain B, Yeast DNA polymerase Eta Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Saccharomyces cervisiae

Immunogen

Synthetic peptide taken within amino acid region 200-300 on Chain A, Yeast DNA polymerase Eta.

Accession #

NCBI1JIH_A


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.70-0.98 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500


Protein

 

Uniprot #

 

Q04049

Overview

DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.

Molecular Function

Damaged DNA binding, Metal ion binding, DNA-directed DNA polymerase activity

Subcellular Location

Nucleus

Expression

Induced by UV radiation and heat shock.  The mRNA is stabilized during stationary phase.

Structure

Interacts with POL30. This interaction is essential for the polymerase eta function.

Alternative Nomenclature

DNA polymerase eta antibody

FLJ16395 antibody

FLJ21978 antibody

POLH antibody

polymerase DNA directed eta antibody

RAD30 antibody

RAD30 homolog A antibody

Xeroderma pigmentosum variant type protein antibody

XPV antibody

   

Protein information supplied by UniProt
 

Accessories

Product Note Status Price
DNA polymerase eta Antibody FITC DNA polymerase eta Antibody FITC
RAD30-FITC $350.00 *
DNA polymerase eta Antibody BIOTIN DNA polymerase eta Antibody BIOTIN
RAD30-BIOTIN $350.00 *
DNA polymerase eta Blocking Peptide DNA polymerase eta Blocking Peptide
P-RAD30 $145.00 *
DNA polymerase eta Positive Control DNA polymerase eta Positive Control
PC-RAD30 $185.00 *
Display accessory details

Browse these categories as well: Epigenetics, Nuclear Signaling Pathways, DNA / RNA, Primaries, DNA Damage Response