Robo3 Antibody BIOTIN

General Information

Product

Robo3 Antibody BIOTIN-Conjugated

Description

BIOTIN-Conjugated Homer protein homolog 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Panda

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human RIG1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

BIOTIN-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Z214

Overview

ostsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release.

Molecular Function

G-protein coupled glutamate receptor binding, identical protein binding, receptor binding

Subcellular Location

Cytoplasm, Cell junction

Expression

Highly expressed in cortex, Purkinje cells of the cerebellum, hippocampus, striatum and olfactory bulb. Isoform 1and isoform 3 are expressed in skeletal and cardiac muscle.

Structure

Interacts with GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. Interacts with IFT57 and OPHN1. Isoform 1 and isoform 2 encode coiled-coil structures that mediate homo- and heteromultimerization.

Alternative Nomenclature

HGPPS antibody

HGPS antibody

RB inhibiting gene 1 antibody

Rbig1 antibody

Retinoblastoma inhibiting gene 1 antibody

Rig1 antibody

Roundabout axon guidance receptor homolog 3 antibody

Roundabout like protein 3 antibody