ROR2 Antibody

Product no.: ROR2-201AP

$285.00

Description

General Information
Product	ROR2 Antibody
Description	Affinity Purified Tyrosine-protein kinase transmembrane receptor ROR2 precursor Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 900-943 on human ROR2 protein.
Accession #	NCBI: NP_004551.2
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q01974
Overview	Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.
Molecular Function	Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase
Subcellular Location	Cell membrane; Single-pass type 1 membrane protein
Expression	Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues.
Structure	Homodimer; promotes osteogenesis. Binds YWHAB. Interacts with WTIP.
Alternative Nomenclature	BDB antibody BDB1 antibody Brachydactyly type B antibody EC 2.7.10.1 antibody MGC163394 antibody Neurotrophic tyrosine kinase, receptor related 2 antibody NTRKR2 antibody Receptor tyrosine kinase-like orphan receptor 2 antibody

Protein information supplied by UniProt