|
General Information
|
|
|
Product
|
ROR2 Antibody
|
|
Description
|
Affinity Purified Tyrosine-protein kinase transmembrane receptor ROR2 precursor Antibody
|
|
Verified Applications
|
ELISA, IHC, IP, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
|
Immunogen
|
Synthetic peptide taken within amino acid region 900-943 on human ROR2 protein.
|
|
Accession #
|
NCBI: NP_004551.2
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.55-0.75 µg/µl in antibody stabilization buffer
|
|
Form
|
Affinity Purified
|
|
Clonality
|
Polyclonal
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
DB
|
1:10,000
|
|
ELISA
|
1:10,000
|
| Immunohistochemistry |
1:50-1:150 |
| Immunoprecipitation |
1:200 |
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
Q01974
|
|
Overview
|
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.
|
|
Molecular Function
|
Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase
|
|
Subcellular Location
|
Cell membrane; Single-pass type 1 membrane protein
|
|
Expression
|
Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues.
|
|
Structure
|
Homodimer; promotes osteogenesis. Binds YWHAB. Interacts with WTIP.
|
|
Alternative Nomenclature
|
BDB antibody
BDB1 antibody
Brachydactyly type B antibody
EC 2.7.10.1 antibody
MGC163394 antibody
Neurotrophic tyrosine kinase, receptor related 2 antibody
NTRKR2 antibody
Receptor tyrosine kinase-like orphan receptor 2 antibody
|
| |
|
ROR2 Antibody FITC
ROR2 Antibody BIOTIN
ROR2 Blocking Peptide
ROR2 Positive Control
