EDG8 Antibody

Product no.: S1P5R-501AP

$285.00

Description

General Information
Product	EDG8 Antibody
Description	Affinity Purified Sphingosine 1-phosphate receptor 5 Antibody
Verified Applications	ELISA, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 380-400 of rat S1P5R/EDG8 protein.
Specificity	Does not cross eact to other Spingosine 1-phosphate receptor subtypes. Labels a strong band of EDG8 of 48-50 kDa. Also labels a 54 kDa band, the identity of this is not known but may represent phosphorylated EDG8.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.52-0.63 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Western Blot	1:500
Protein
Uniprot #	Q9JKM5
Overview	Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins.
Molecular Function	G-protein coupled receptor, Receptor, Transducer
Subcellular Location	Cell membrane; Multi-pass membrane protein
Expression	Found almost exclusively in brain and skin. Ubiquitously detected in different brain regions with very prominent expression in lower brain regions such as the midbrain, pons, medulla, and spinal cord. Expressed predominantly within white matter tracts of
Alternative Nomenclature	EDG 8 antibody Endothelial differentiation G protein coupled receptor 8 antibody Endothelial differentiation sphingolipid G protein coupled receptor 8 antibody S1P receptor 5 antibody S1P receptor Edg 8 antibody Sphingosine 1 Phosphate Receptor 5 antibody Sphingosine 1-phosphate receptor Edg-8 antibody SPPR2 antibody

Protein information supplied by UniProt