ARTS Antibody

General Information

Product

ARTS Antibody Affinity Purified

Description

Affinity Purified Septin-4 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on SEPT4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-075 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O43236

Overview

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.

Molecular Function

GTPase activity, structural molecule activity, GTP binding

Subcellular Location

Cytoplasm, cytoskeleton. (Note: In platelets, found in areas surrounding alpha-granules)

Expression

Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in plate

Alternative Nomenclature

Apoptosis Related Protein TGFb Signalling antibody

ARTS antibody

Bradeion beta antibody

Brain protein H5 antibody

CE5B3 antibody

CE5B3 beta antibody

cell division control-related protein 2 antibody

cerebral protein 7 antibody

H5 antibody

hCDCREL-2 antibody

Hucep 7 antibody

MART antibody

Peanut-like protein 2 antibody

PNUTL2 antibody

SEP4 antibody

SEPT4 antibody

Septin-4 antibody