SERINC5 Antibody

Product no.: SERC5-501AP

$285.00

Description
QA_1

General Information
Product	SERINC5 Antibody
Description	Affinity Purified Serine incorporator 5 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 270-320 on human Serine incorporator 5 protein.
Specificity	This antibody will detect the extracellular domain of SERINC5 protein.
Accession #	NCBI: XP_011541606
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	UPI0005D01C8F
Overview	Restriction factor required to restrict infectivity of gammaretroviruses, such as HIV-1: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).
Molecular Function	L-serine transmembrane transporter activity
Subcellular Location	Cell membrane; Multi-pass membrane
Expression	Highly expressed in placenta, skeletal muscle, spleen, thymus, testis and peripheral leukocyte and is expressed weakly in the heart, liver and fetal brain.
Structure	Belongs to the TDE1 family
Alternative Nomenclature	C5orf12 antibody SERC5_HUMAN antibody SERINC5 antibody Serine incorporator 5 antibody TPO1 antibody

Protein information supplied by UniProt