|
General Information
|
|
|
Product
|
SESN1 Antibody
|
|
Description
|
Affinity Purified Sestrin-1 Antibody
|
|
Verified Applications
|
ELISA, IHC, IP, WB
|
|
Host
|
Rabbit
|
|
Species Cross Reactivity
|
Human, Mouse, Rat
|
|
Immunogen
|
Synthetic peptide taken within amino acid region 1-50 on human SESN1 protein.
|
|
Physical Properties
|
|
|
Quantity
|
100 µg
|
|
Volume
|
200 µl
|
|
Concentration
|
0.55 µg/µl in antibody stabilization buffer
|
|
Clonality
|
Polyclonal
|
|
Storage
|
-20⁰C for long term storage
|
|
Application Protocol
|
|
DB
|
1:10,000
|
|
ELISA
|
1:10,000
|
| Immunohistochemistry |
1:50-1:150 |
| Immunoprecipitation |
1:200 |
|
Western Blot
|
1:500
|
|
Protein
|
|
Uniprot #
|
Q9Y6P5
|
|
Overview
|
Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.
|
|
Molecular Function
|
Cell cycle arrest; Cellular response to DNA damage stimulus; Gene expression; Regulation of protein kinase B signaling; Transcription initation from RNA polymerase II promoter; Regulation of response to reactive oxygen species; Negative regulation of cell.
|
|
Subcellular Location
|
Nucleus
|
|
Expression
|
Widely Expressed
|
|
Structure
|
Belongs to the Sestrin family.
|
|
Alternative Nomenclature
|
1110002G11Rik antibody
AU044290 antibody
p53 activated gene 26 antibody
p53 regulated PA26 nuclear protein antibody
PA26 antibody
RP11-787I22.1 antibody
sesn1 antibody
SEST1 antibody
Sestrin-1 antibody
|
| |
|
SESN1 Antibody FITC
SESN1 Antibody BIOTIN
SESN1 Blocking Peptide
SESN1 Positive Control
