General Information
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Product
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SFRP2 Antibody
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Description
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Affinity Purified Secreted frizzled-related protein 2 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 225-295 on human SFRP2.
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Accession #
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GenBank: AAH08666.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DOT Blot
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q96HF1
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Overview
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Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
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Molecular Function
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Endopeptidase activator activity, integrin binding, PDZ domain binding, Wnt-activated receptor activity, fibronectin binding, receptor agonist activity, Wnt-protein binding
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Subcellular Location
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Secreted
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Expression
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Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
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Alternative Nomenclature
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AI851596 antibody
Frizzled related protein 2 antibody
FRP2 antibody
SARP1 antibody
SDF5 antibody
Secreted apoptosis related protein 1 antibody
Secreted frizzled-related protein 2 antibody
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