Slingshot homolog 1 Antibody

General Information

Product

Slingshot homolog 1 Antibody Affinity Purified

Description

Affinity Purified Protein phosphatase Slingshot homolog 1 isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on Slingshot homolog 1 protein.

Accession #

NCBI:  NP_061857.3

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8WYL5

Overview

Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.

Molecular Function

Hydrolase, protein phosphatase

Subcellular Location

Cytoplasm, cytoskeleton, cell projection, lamellipodium, cleavage furrow, midbody. (Note: Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at site of cell locomotion. Also localized to

Alternative Nomenclature

AW551225 antibody

Coro1c antibody

coronin, actin binding protein 1C antibody

Gm1394 antibody

Gm1395 antibody

Protein phosphatase Slingshot homolog 1 antibody

slingshot like 1 antibody

SSH1 antibody