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General Information
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Product
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SOX10 Antibody BIOTIN
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Description
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BIOTIN-Conjugated Transcription Factor SOX-10 Antibody C-epitope
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 400-450 on human Transcription Factor SOX-10 protein.
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Accession #
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NCBI: NP_008872.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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1:50-1:100 |
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P56693
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Overview
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Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia.
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Molecular Function
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Chromatin binding; Identical protein binding; RNA polymerase II transcription factor binding transcription factor activity invovled in positive regulation of transcription
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Subcellular Location
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Cytoplasm; Nucleus
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Expression
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Expressed in fetal brain and in adult brain, heart, small intestine and colon.
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Structure
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Contains 1 HMG box DNA-binding domain.
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Alternative Nomenclature
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DOM
Dominant megacolon mouse human homolog of
MGC15649
PCWH
SOX 10
SRY (sex determining region Y) box 10
SRY box 10
SRY box containing gene 10
SRY related HMG box gene 10
Transcription factor SOX 10
WS2E
WS4
WS4C
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SOX10 Blocking Peptide
SOX10 Antibody
SOX10 Antibody FITC
SOX10 Positive Control
