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General Information
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Product
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STAT3 Antibody
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Description
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Affinity Purified Signal transducer and activator of transcription Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 700-750 on human STAT3 protein.
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Accession #
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NCBI: NP_644805
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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P40763
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Overview
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Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.
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Molecular Function
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Activator, calcium ion binding, DNA binding
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Subcellular Location
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Cytoplasm. Nucleus
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Expression
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Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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Structure
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Forms a homodimer or a heterodimer with a related family member (at least STAT1). Interacts with IL31RA, NCOA1, PELP1, SIPAR, SOCS7, STATIP1 and TMF1. Interacts with HCV core protein. Interacts with IL23R in presence of IL23.
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Alternative Nomenclature
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Acute Phase Response Factor antibody
APRF antibody
DNA binding protein APRF antibody
HIES antibody
Signal transducer and activator of transcription 3 (acute phase response factor) antibody
STAT 3 antibody
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STAT3 Antibody BIOTIN
STAT3 Antibody FITC
STAT3 Blocking Peptide
STAT3 Positive Control
